Keith P Klugman Selected Research

Pneumococcal Infections

1/2021	Triumph of Pneumococcal Conjugate Vaccines: Overcoming a Common Foe.
1/2021	Streptococcus pneumoniae genomic datasets from an Indian population describing pre-vaccine evolutionary epidemiology using a whole genome sequencing approach.
1/2021	Pneumococcal Conjugate Vaccine Protection against Coronavirus-Associated Pneumonia Hospitalization in Children Living with and without HIV.
1/2020	Epidemiology of invasive bacterial infections in pneumococcal conjugate vaccine-vaccinated and -unvaccinated children under 5 years of age in Soweto, South Africa: a cohort study from a high-HIV burden setting.
5/2019	International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.
1/2019	Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.
8/2017	Imputing the Direct and Indirect Effectiveness of Childhood Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease by Surveying Temporal Changes in Nasopharyngeal Pneumococcal Colonization.
1/2017	Strain Level Streptococcus Colonization Patterns during the First Year of Life.
1/2017	Estimated severe pneumococcal disease cases and deaths before and after pneumococcal conjugate vaccine introduction in children younger than 5 years of age in South Africa.
1/2017	Effectiveness of the 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in South African children: a case-control study.

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Keith P Klugman Research Topics

Disease

48	Pneumococcal Infections 01/2021 - 09/2002
36	Pneumonia (Pneumonitis) 10/2021 - 05/2002
23	Infections 01/2021 - 04/2002
20	Human Influenza (Influenza) 01/2020 - 10/2008
16	Pneumococcal Pneumonia 01/2017 - 08/2004
7	Bacterial Infections (Bacterial Infection) 01/2021 - 01/2002
7	Coinfection 01/2014 - 11/2002
6	Respiratory Tract Infections (Respiratory Tract Infection) 01/2021 - 03/2003
6	HIV Infections (HIV Infection) 01/2020 - 10/2003
6	Meningitis 10/2019 - 01/2002
5	Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) 01/2021 - 02/2007
5	Diphtheria 12/2016 - 02/2002
4	Tetanus 12/2016 - 02/2002
4	Whooping Cough (Pertussis) 12/2016 - 02/2002
4	Bacterial Meningitis 12/2013 - 01/2002
4	Tuberculosis (Tuberculoses) 10/2012 - 11/2003
4	Bacteremia 08/2004 - 07/2003
3	Otitis Media 12/2018 - 03/2003
3	Trachoma 06/2016 - 08/2009
2	COVID-19 12/2020 - 01/2020
2	Meningococcal Infections 10/2019 - 01/2014
2	Opportunistic Infections (Opportunistic Infection) 01/2017 - 01/2011
2	Typhoid Fever (Typhoid) 01/2016 - 04/2014
2	Virus Diseases (Viral Diseases) 02/2014 - 10/2011
2	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 05/2009 - 03/2008
2	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 11/2002 - 05/2002
1	Communicable Diseases (Infectious Diseases) 01/2020
1	Stillbirth 01/2019
1	Fetal Death 01/2019
1	Spontaneous Abortion (Miscarriage) 01/2019
1	Premature Birth (Birth, Premature) 01/2019
1	Salmonella Infections (Salmonellosis) 01/2017
1	Perinatal Death 12/2016
1	Empyema 05/2014
1	Paramyxoviridae Infections (Parainfluenza) 01/2014
1	Chronic Disease (Chronic Diseases) 03/2013
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2011
1	Pulmonary Tuberculosis 12/2010
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2009
1	Lung Diseases (Lung Disease) 01/2009
1	Bacterial Pneumonia 12/2008
1	Apnea 06/2008
1	Vaccine-Preventable Diseases 05/2007

Drug/Important Bio-Agent (IBA)

56	Conjugate VaccinesIBA 10/2021 - 02/2002
46	VaccinesIBA 10/2021 - 02/2002
24	Anti-Bacterial Agents (Antibiotics)IBA 12/2020 - 01/2002
9	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 01/2021 - 05/2006
7	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2020 - 05/2011
7	Penicillins (Penicillin)FDA Link 12/2013 - 10/2003
7	FluoroquinolonesIBA 01/2011 - 01/2002
5	C-Reactive ProteinIBA 06/2017 - 02/2005
4	ProcalcitoninIBA 01/2021 - 02/2005
4	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 06/2014 - 01/2002
4	Proteins (Proteins, Gene)FDA Link 05/2006 - 05/2002
3	AntigensIBA 01/2017 - 04/2014
3	Azithromycin (Zithromax)FDA LinkGeneric 06/2016 - 08/2009
3	Polysaccharides (Glycans)IBA 04/2014 - 05/2002
3	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 03/2012 - 11/2002
3	QuinolonesIBA 01/2011 - 01/2002
3	CRM197 (non-toxic variant of diphtheria toxin)IBA 12/2004 - 04/2002
2	Bacterial VaccinesIBA 12/2018 - 12/2010
2	Coloring Agents (Dyes)IBA 01/2017 - 08/2014
2	AntibodiesIBA 12/2016 - 04/2014
2	Oxygen (Dioxygen)IBA 12/2016 - 01/2014
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 09/2014 - 01/2014
2	CI 22IBA 05/2014 - 05/2006
2	Cefotaxime (Kendrick)FDA LinkGeneric 12/2013 - 01/2004
2	Amoxicillin (Wymox)FDA LinkGeneric 12/2013 - 12/2007
2	Levofloxacin (Levaquin)FDA Link 05/2009 - 03/2008
2	MacrolidesIBA 07/2008 - 09/2007
2	Heptavalent Pneumococcal Conjugate Vaccine (Prevnar)IBA 05/2007 - 09/2002
2	beta-Lactamases (beta-Lactamase)IBA 07/2004 - 01/2004
2	beta Lactam AntibioticsIBA 01/2004 - 07/2003
1	insulin receptor-related receptor (IRR)IBA 01/2020
1	MenAfriVacIBA 10/2019
1	P-2 (P 2)IBA 01/2016
1	polysaccharide C-substance (Streptococcus)IBA 08/2014
1	Biomarkers (Surrogate Marker)IBA 08/2014
1	Immunoglobulin G (IgG)IBA 04/2014
1	FluMistIBA 02/2014
1	Viral VaccinesIBA 02/2014
1	Meningococcal Vaccines (Meningococcal Vaccine)IBA 01/2014
1	DNA (Deoxyribonucleic Acid)IBA 01/2014
1	Streptococcus pneumoniae plY proteinIBA 09/2013
1	Biological ProductsIBA 10/2011
1	Capsules (Microcapsules)IBA 09/2011
1	Carrier Proteins (Binding Protein)IBA 09/2011
1	ORALIT (ORS)IBA 05/2011
1	Cephalosporins (Cephalosporin Antibiotics)IBA 02/2009
1	GoldIBA 01/2009
1	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 12/2007
1	aerobactinIBA 07/2007

Therapy/Procedure

12	Therapeutics 01/2020 - 01/2002
2	Antibiotic Prophylaxis 01/2018 - 01/2012
2	Highly Active Antiretroviral Therapy (HAART) 01/2011 - 02/2007
1	Art Therapy 01/2017
1	Prenatal Care (Care, Prenatal) 12/2016
1	Treatment Delay 06/2016
1	Medical Day Care (Partial Hospitalization) 01/2015
1	Drug Prescriptions 06/2005